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Literature summary extracted from

  • Retzios, A.D.; Markland, F.S.
    A direct-acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix: effects on various components of the human blood coagulation and fibrinolysis systems (1988), Thromb. Res., 52, 541-552.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.72 Agkistrodon contortrix contortrix
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.72 venom
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Agkistrodon contortrix contortrix
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.72 Fibrin Aalpha-chain + H2O human, cleavage at Lys413-Lys414, the Bbeta-chain is cleaved more slowly and the gamma-chain is minimally affected Agkistrodon contortrix contortrix ?
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?
3.4.24.72 Fibrinogen Aalpha-chain + H2O human Agkistrodon contortrix contortrix ?
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?
3.4.24.72 Fibrinogen Aalpha-chain + H2O cleavage at Lys413-Leu414 (initial cleavage) Agkistrodon contortrix contortrix ?
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?
3.4.24.72 Fibrinogen Aalpha-chain + H2O the Bbeta-chain is cleaved more slowly and the gamma-chain is minimally affected Agkistrodon contortrix contortrix ?
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?
3.4.24.72 additional information does not activate protein C Agkistrodon contortrix contortrix ?
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?
3.4.24.72 additional information does not activate plasminogen Agkistrodon contortrix contortrix ?
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?